منابع مشابه
Asymmetric dimethylarginine (ADMA), symmetric dimethylarginine (SDMA) and homoarginine (hArg): the ADMA, SDMA and hArg paradoxes
NG-Methylation of L-arginine (Arg) residues in certain proteins by protein arginine methyltransferases and subsequent proteolysis yields NG-monomethyl-L-arginine (MMA), NG,NG-dimethyl-L-arginine (asymmetric dimethylarginine, ADMA) and NG,N'G-dimethyl-L-arginine (symmetric dimethylarginine, SDMA). Biological MMA, ADMA and SDMA occur as free acids in the nM-range and as residues of proteins of la...
متن کامل[Hyperhomocysteinemia and cardiometabolic risk].
Hyperhomocysteinemia, when considered as a causal factor of vascular diseases, has been subject of much discussion. Case-control, retrospective and prospective studies have identified a relationship between high plasma concentrations of homocysteine and vascular disease. The aim of the present review was to better understand the interrelation between plasma concentrations of homocysteine and va...
متن کاملDDAH says NO to ADMA.
Endothelium-derived nitric oxide (NO) is vasoprotective, as it enhances endothelial cell survival and proliferation, inhibits the excessive proliferation of vascular smooth muscle cells, and suppresses the adhesion of platelets and inflammatory cells to the vessel wall.1 Substantial evidence from preclinical studies and human research indicates that impairment of the endothelial NO synthase (NO...
متن کاملHyperhomocysteinemia and Left Ventricular Thrombus
© 2017 Annals of Cardiac Anaesthesia | Published by Wolters Kluwer Medknow The Editor, We read with great interest the article – Left ventricular mass: A tumor or a thrombus diagnostic dilemma, describing the narrated differential diagnosis.[1] Left ventricular thrombus formation is commonly observed in patients with myocardial infarction with systolic dysfunction. However, it becomes difficult...
متن کاملHyperhomocysteinemia and Atherosclerosis – an Overveiw
Indians are reported to have a very high prevalence of premature Coronary artery disease (CAD). A link between plasma homocysteine concentrations with vascular disease was first suggested by the observation made in patients with homocystinuria having arteriosclerosis. The recent interest in this topic has been generated by the evidence, that people with hyperhomocysteinemia have an increased ri...
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ژورنال
عنوان ژورنال: Vascular Medicine
سال: 2005
ISSN: 1358-863X,1477-0377
DOI: 10.1191/1358863x05vm599oa